Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Iva-Val-Val-Sta-Ala-Sta | - |
Plasmodium falciparum | |
Ro40-4388 | - |
Plasmodium falciparum | |
Ro40-5576 | - |
Plasmodium falciparum |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.006 | - |
Lys-Glu-Leu-Val-Phe-Phe(NO2)-Ala-Leu-Lys | pH 4.4, 37°C, recombinant enzyme | Plasmodium falciparum | |
0.006 | - |
Leu-Glu-Arg-Ile-Phe-Phe(NO2)-Ser-Phe | pH 4.4, 37°C, naturally occuring enzyme | Plasmodium falciparum | |
0.007 | - |
Lys-Glu-Phe-Val-Phe-Phe(NO2)-Ala-Leu-Lys | pH 4.4, 37°C, naturally occuring enzyme or recombinant enzyme | Plasmodium falciparum | |
0.008 | - |
Lys-Glu-Leu-Val-Phe-Phe(NO2)-Ala-Leu-Lys | pH 4.4, 37°C, naturally occuring enzyme | Plasmodium falciparum | |
0.01 | - |
Leu-Glu-Arg-Ile-Phe-Phe(NO2)-Ser-Phe | pH 4.4, 37°C, recombinant enzyme | Plasmodium falciparum | |
0.01 | - |
Lys-Glu-Phe-Val-Phe-Phe(NO2)-Arg-Leu-Lys | pH 4.4, 37°C, recombinant enzyme | Plasmodium falciparum |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Plasmodium falciparum | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Leu-Glu-Arg-Ile-Phe-Phe(NO2)-Ser-Phe + H2O | - |
Plasmodium falciparum | Leu-Glu-Arg-Ile-Phe + Phe(NO2)-Ser-Phe | - |
? | |
Lys-Glu-Leu-Val-Phe-Phe(NO2)-Ala-Leu-Lys + H2O | - |
Plasmodium falciparum | Lys-Glu-Leu-Val-Phe + Phe(NO2)-Ala-Leu-Lys | - |
? | |
Lys-Glu-Phe-Asn-Phe-Phe(NO2)-Ala-Leu-Lys + H2O | - |
Plasmodium falciparum | Lys-Glu-Phe-Asn-Phe + Phe(NO2)-Ala-Leu-Lys | - |
? | |
Lys-Glu-Phe-Val-Phe-Phe(NO2)-Ala-Leu-Lys + H2O | - |
Plasmodium falciparum | Lys-Glu-Phe-Val-Phe + Phe(NO2)-Ala-Leu-Lys | - |
? | |
Lys-Glu-Phe-Val-Phe-Phe(NO2)-Arg-Leu-Lys + H2O | - |
Plasmodium falciparum | Lys-Glu-Phe-Val-Phe + Phe(NO2)-Arg-Leu-Lys | - |
? |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
1.5 | - |
Lys-Glu-Leu-Val-Phe-Phe(NO2)-Ala-Leu-Lys | pH 4.4, 37°C, recombinant enzyme | Plasmodium falciparum | |
6 | - |
Lys-Glu-Leu-Val-Phe-Phe(NO2)-Ala-Leu-Lys | pH 4.4, 37°C, naturally occuring enzyme | Plasmodium falciparum | |
7 | - |
Lys-Glu-Phe-Asn-Phe-Phe(NO2)-Ala-Leu-Lys | pH 4.4, 37°C, recombinant enzyme | Plasmodium falciparum | |
10 | - |
Leu-Glu-Arg-Ile-Phe-Phe(NO2)-Ser-Phe | pH 4.4, 37°C, naturally occuring enzyme | Plasmodium falciparum | |
11 | - |
Lys-Glu-Phe-Val-Phe-Phe(NO2)-Arg-Leu-Lys | pH 4.4, 37°C, recombinant enzyme | Plasmodium falciparum | |
13 | - |
Leu-Glu-Arg-Ile-Phe-Phe(NO2)-Ser-Phe | pH 4.4, 37°C, recombinant enzyme | Plasmodium falciparum | |
17 | - |
Lys-Glu-Phe-Val-Phe-Phe(NO2)-Ala-Leu-Lys | pH 4.4, 37°C, recombinant enzyme | Plasmodium falciparum | |
19 | - |
Lys-Glu-Phe-Val-Phe-Phe(NO2)-Ala-Leu-Lys | pH 4.4, 37°C, naturally occuring enzyme | Plasmodium falciparum |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | Ki value for Iva-Val-Val-Sta-Ala-Sta is below 0.1 nM | Plasmodium falciparum | |
0.00025 | - |
Ro40-5576 | - |
Plasmodium falciparum | |
0.0005 | - |
Ro40-4388 | pH 4.4, 37°C | Plasmodium falciparum |