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Literature summary for 3.4.23.22 extracted from

  • Koester, H.; Craan, T.; Brass, S.; Herhaus, C.; Zentgraf, M.; Neumann, L.; Heine, A.; Klebe, G.
    A small nonrule of 3 compatible fragment library provides high hit rate of endothiapepsin crystal structures with various fragment chemotypes (2011), J. Med. Chem., 54, 7784-7796.
    View publication on PubMed
Search for more literature for 3.4.23.22

Crystallization (Commentary)

Crystallization (Comment) Organism
sitting drop vapor diffusion method, using 0.1 M NH4Ac, 0.1 M acetate buffer, pH 4.6, and 26% (w/v) PEG 4000 Cryphonectria parasitica

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0016
-
 Abz-Thr-Ile-Nle-4-nitro-Phe-Gln-Arg-NH2 in 0.1 M acetate buffer, pH 4.6, containing 0.01% (v/v) Tween 20, temperature not specified in the publication Cryphonectria parasitica

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
34000
-
 x * 34000 Cryphonectria parasitica

Organism

Organism UniProt Comment Textmining
Cryphonectria parasitica P11838
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Cryphonectria parasitica

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Abz-Thr-Ile-Nle-4-nitro-Phe-Gln-Arg-NH2 + H2O
-
 Cryphonectria parasitica Abz-Thr-Ile-Nle + 4-nitro-Phe-Gln-Arg-NH2
-
 ?

Subunits

Subunits Comment Organism
? x * 34000 Cryphonectria parasitica