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Literature summary for 3.4.23.19 extracted from

  • Komatsu, S.; Nishii, W.; Sasaki, H.; Muramatsu, T.; Tanokura, M.
    Substrate specificity of non-pepsin-type acid proteinase, Aspergillus niger proteinase A (1998), Adv. Exp. Med. Biol., 436, 345-348.
    View publication on PubMed
Search for more literature for 3.4.23.19

Inhibitors

Inhibitors Comment Organism Structure
additional information insensitive to pepstatin, diazoacetyl-DL-norleucine methyl ester, and 1,2-epoxy-3-(p-nitrophenoxy)propane Aspergillus niger

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.016
-
 RGFFHTPRA pH 1.8, 37°C Aspergillus niger
0.016
-
 RGFMTPRA pH 1.8, 37°C Aspergillus niger
0.07
-
 RGFFTPRA pH 1.8, 37°C Aspergillus niger
0.33
-
 RGFFYTPRA pH 1.8, 37°C Aspergillus niger

Organism

Organism UniProt Comment Textmining
Aspergillus niger
-
 var.macrosporus
-

Purification (Commentary)

Purification (Comment) Organism
-
 Aspergillus niger

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information enzyme seems to cleave only peptides which contain large residues at p2 site, hardly influenced by the charges of the residues Aspergillus niger ?
-
 ?
RGFFHTPRA + H2O
-
 Aspergillus niger ?
-
 ?
RGFFTPRA + H2O
-
 Aspergillus niger ?
-
 ?
RGFFYTPRA + H2O
-
 Aspergillus niger ?
-
 ?
RGFMTPRA + H2O
-
 Aspergillus niger ?
-
 ?

Synonyms

Synonyms Comment Organism
Proteinase A
-
 Aspergillus niger

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.19
-
 RGFFHTPRA pH 1.8, 37°C Aspergillus niger
0.26
-
 RGFMTPRA pH 1.8, 37°C Aspergillus niger
0.48
-
 RGFFTPRA pH 1.8, 37°C Aspergillus niger
0.54
-
 RGFFYTPRA pH 1.8, 37°C Aspergillus niger
6.08
-
 RGFFYTPRA pH 1.8, 37°C Aspergillus niger