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Literature summary for 3.4.23.16 extracted from
- Monitoring inhibitor-induced conformational population shifts in HIV-1 protease by pulsed EPR spectroscopy (2009), Biochemistry, 48, 8765-8767.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| amprenavir | - |
Human immunodeficiency virus 1 |  |
| atazanavir | - |
Human immunodeficiency virus 1 | |
| darunavir | - |
Human immunodeficiency virus 1 | |
| indinavir | - |
Human immunodeficiency virus 1 | |
| lopinavir | - |
Human immunodeficiency virus 1 | |
| nelfinavir | - |
Human immunodeficiency virus 1 | |
| ritonavir | - |
Human immunodeficiency virus 1 | |
| saquinavir | - |
Human immunodeficiency virus 1 | |
| tipranavir | - |
Human immunodeficiency virus 1 | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Human immunodeficiency virus 1 | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| HIV-1 protease | pentamutated protease: subtype B PMPR, K55C, D25N | Human immunodeficiency virus 1 |
| HIV-1PR | - |
Human immunodeficiency virus 1 |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.00000001 | - |
darunavir | - |
Human immunodeficiency virus 1 | |
| 0.000000019 | - |
tipranavir | - |
Human immunodeficiency virus 1 | |
| 0.00000005 | - |
lopinavir | - |
Human immunodeficiency virus 1 | |
| 0.00000017 | - |
amprenavir | - |
Human immunodeficiency virus 1 | |
| 0.00000048 | - |
atazanavir | - |
Human immunodeficiency virus 1 | |
| 0.0000007 | - |
ritonavir | - |
Human immunodeficiency virus 1 | |
| 0.0000012 | - |
nelfinavir | - |
Human immunodeficiency virus 1 | |
| 0.0000013 | - |
saquinavir | - |
Human immunodeficiency virus 1 | |
| 0.0000039 | - |
indinavir | - |
Human immunodeficiency virus 1 | |
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