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BRENDA support

Literature summary for 3.4.23.15 extracted from

  • Doulton, T.W.; MacGregor, G.A.
    Combination renin-angiotensin system blockade with the renin inhibitor aliskiren in hypertension (2009), J. Renin Angiotensin Aldosterone Syst., 10, 185-189.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
aliskiren non-peptide, orally active, selective renin inhibitor Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
angiotensinogen + H2O Homo sapiens
-
angiotensin I + angiotensinogen propeptide
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood plasma
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
angiotensinogen + H2O
-
Homo sapiens angiotensin I + angiotensinogen propeptide
-
?