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Literature summary for 3.4.23.15 extracted from

  • Ayalasomayajula, S.; Yeh, C.M.; Vaidyanathan, S.; Flannery, B.; Dieterich, H.A.; Howard, D.; Bedigian, M.P.; Dole, W.P.
    Effects of aliskiren, a direct renin inhibitor, on cardiac repolarization and conduction in healthy subjects (2008), J. Clin. Pharmacol., 48, 799-811.
    View publication on PubMed

Application

Application Comment Organism
pharmacology aliskiren at the highest approved dose of 300 mg once daily for 7 days and a 4-fold higher dose has no effect on cardiac repolarization or conduction in healthy volunteers Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
aliskiren aliskiren at the highest approved dose of 300 mg once daily for 7 days and a 4-fold higher dose has no effect on cardiac repolarization or conduction in healthy volunteers Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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