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Literature summary for 3.4.22.B74 extracted from

  • Kim, K.I.; Baek, S.H.; Jeon, Y.J.; Nishimori, S.; Suzuki, T.; Uchida, S.; Shimbara, N.; Saitoh, H.; Tanaka, K.; Chung, C.H.
    A new SUMO-1-specific protease, SUSP1, that is highly expressed in reproductive organs (2000), J. Biol. Chem., 275, 14102-14106.
    View publication on PubMed
Search for more literature for 3.4.22.B74

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm SUSP1 is exclusively localized to the cytoplasm of NIH3T3 and HeLa cells Homo sapiens 5737
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
126116
-
 x * 126116, calculated from sequence Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9GZR1
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain little activity Homo sapiens
-
colon reproductive organs, such as testis, ovary, and prostate, contain much higher amounts of SUSP1 mRNA than colon and peripheral blood leukocyte Homo sapiens
-
HeLa cell
-
 Homo sapiens
-
leukocyte reproductive organs, such as testis, ovary, and prostate, contain much higher amounts of SUSP1 mRNA than colon and peripheral blood leukocyte Homo sapiens
-
additional information no or little SUSP1 mRNA in liver, lung, kidney, pancreas, spleen, thymus, heart, and skeletal muscle Homo sapiens
-
ovary reproductive organs, such as testis, ovary, and prostate, contain much higher amounts of SUSP1 mRNA than colon and peripheral blood leukocyte Homo sapiens
-
prostate reproductive organs, such as testis, ovary, and prostate, contain much higher amounts of SUSP1 mRNA than colon and peripheral blood leukocyte Homo sapiens
-
testis reproductive organs, such as testis, ovary, and prostate, contain much higher amounts of SUSP1 mRNA than colon and peripheral blood leukocyte Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(SUMO-1)-beta-galactosidase conjugate + H2O SUSP1 expressed in Escherichia coli cells efficiently releases SUMO-1 from SUMO-1-beta-galactosidase fusion but not from other ubiquitin-like protein fusions, including Smt3-beta-galactosidase Homo sapiens SUMO-1 + beta-galactosidase
-
 ?
additional information SUSP1 expressed in Escherichia coli cells efficiently releases SUMO-1 from SUMO-1-beta-galactosidase fusion but not from other ubiquitin-like protein fusions, including Smt3zb-galactosidase, suggesting its role in the generation of matured SUMO-1 specifically from its precursors Homo sapiens ?
-
 ?
SUMO-1 precursor + H2O
-
 Homo sapiens SUMO-1 + His-Ser-Thr-Val
-
 ?

Subunits

Subunits Comment Organism
? x * 126116, calculated from sequence Homo sapiens

Synonyms

Synonyms Comment Organism
SUSP1
-
 Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.8
-
 assay at Homo sapiens