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Literature summary for 3.4.22.B72 extracted from
- RanBP2 and SENP3 function in a mitotic SUMO2/3 conjugation-deconjugation cycle on Borealin (2009), Mol. Biol. Cell, 20, 410-418.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (SUMO2)-Borealin protein + H2O | Homo sapiens | Borealin is dynamically modified by SUMO2/3 during mitosis | SUMO2 + Borealin protein | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | Q9H4L4 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (SUMO2)-Borealin protein + H2O | - |
Homo sapiens | SUMO2 + Borealin protein | - |
? | |
| (SUMO2)-Borealin protein + H2O | Borealin is dynamically modified by SUMO2/3 during mitosis | Homo sapiens | SUMO2 + Borealin protein | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| sentrin-specific protease 3 | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | upon depletion of SENP3 the amount of Borealin-SUMO2/3 conjugates is significantly increased | Homo sapiens |
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