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Literature summary for 3.4.22.B70 extracted from
- SENP1 enhances androgen receptor-dependent transcription through desumoylation of histone deacetylase 1 (2004), Mol. Cell. Biol., 24, 6021-6028.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (SUMO-1)-histone deacetylase 1 conjugate + H2O | Homo sapiens | SENP1 regulates that androgen receptor-dependent transcription through desumoylation of histone deacetylase 1 (HDAC1) | SUMO-1 + histone deacetylase 1 | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | Q9P0U3 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (SUMO-1)-histone deacetylase 1 conjugate + H2O | - |
Homo sapiens | SUMO-1 + histone deacetylase 1 | - |
? | |
| (SUMO-1)-histone deacetylase 1 conjugate + H2O | SENP1 regulates that androgen receptor-dependent transcription through desumoylation of histone deacetylase 1 (HDAC1) | Homo sapiens | SUMO-1 + histone deacetylase 1 | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| SENP1 | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | SENP1 can regulate that androgen receptor-dependent transcription through desumoylation of histone deacetylase | Homo sapiens |
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Release 2023.1 (January 2023)
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