Literature summary for 3.4.22.B70 extracted from

Cheng, J.; Kang, X.; Zhang, S.; Yeh, E.T.
SUMO-specific protease 1 is essential for stabilization of HIF1alpha during hypoxia (2007), Cell, 131, 584-595.

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	P59110	-	-

General Information	Comment	Organism
physiological function	SENP1 plays a key role in the regulation of the hypoxic response through regulation of HIF1alpha stability and SUMOylation can serve as a direct signal for ubiquitin-dependent degradation	Mus musculus

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Release 2023.1 (January 2023)