Literature summary for 3.4.22.B67 extracted from

Jongjitwimol, J.; Feng, M.; Zhou, L.; Wilkinson, O.; Small, L.; Baldock, R.; Taylor, D.L.; Smith, D.; Bowler, L.D.; Morley, S.J.; Watts, F.Z.
The S. pombe translation initiation factor eIF4G is SUMOylated and associates with the SUMO protease Ulp2 (2014), PLoS ONE, 9, e94182.

Search for more literature for 3.4.22.B67

Cloned(Commentary)

Cloned (Comment)	Organism
recombinant expression of TAP-tagged enzyme	Schizosaccharomyces pombe

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
nucleus	isozyme Ulp2 is located mainly within the nucleus	Schizosaccharomyces pombe	5634	-

Organism

Organism	UniProt	Comment	Textmining
Schizosaccharomyces pombe	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
recombinant TAP-tagged enzyme by affinity chromatography, two translation initiation factors, eIF4G and eIF3h, co-purify with Ulp2 may be through the interaction of Ulp2 with other member(s) of the eIF3 complex	Schizosaccharomyces pombe

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
sumoylated human eIF4GI + H2O	translation initiation factor and scaffold protein eIF4G is SUMOylated and associates with the SUMO protease Ulp2, partial co-localisation of recombinant human eIF4G and SUMO in stressed HeLa cells	Schizosaccharomyces pombe	?	-	?

Synonyms

Synonyms	Comment	Organism
SUMO protease	-	Schizosaccharomyces pombe
Ulp2	-	Schizosaccharomyces pombe

Temperature Optimum [°C]

Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
20	-	assay at	Schizosaccharomyces pombe

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Release 2023.1 (January 2023)