Literature summary for 3.4.22.B67 extracted from

Mullen, J.R.; Das, M.; Brill, S.J.
Genetic evidence that polysumoylation bypasses the need for a SUMO-targeted Ub ligase (2011), Genetics, 187, 73-87.

Search for more literature for 3.4.22.B67

Organism

Organism	UniProt	Comment	Textmining
Saccharomyces cerevisiae	P40537	-	-

Synonyms

Synonyms	Comment	Organism
Ulp2	-	Saccharomyces cerevisiae
ULP2 SUMO isopeptidase	-	Saccharomyces cerevisiae

General Information

General Information	Comment	Organism
malfunction	deletion of ULP2 promotes the accumulation of poly-SUMO chains and suppresses sgs1DELRA slx5D synthetic lethality and the slx5DELTA sporulation defect. It is speculated that the loss of ULP2 suppresses the toxicity of the sumoylated proteins that accumulate in slx5D-slx8D cells by permitting the extension of poly-SUMO chains on specific target proteins	Saccharomyces cerevisiae

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Release 2023.1 (January 2023)