Cloned (Comment) | Organism |
---|---|
expression in Saccharomyces cerevisiae | Fasciola hepatica |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0155 | - |
benzyloxycarbonyl-Phe-Arg-7-amido-4-methylcoumarin | FhCatL2 | Fasciola hepatica | |
0.0327 | - |
tosyl-Gly-Phe-Arg-7-amido-4-methylcoumarin | FhCatL2 | Fasciola hepatica | |
0.0483 | - |
tosyl-Gly-Pro-Arg-7-amido-4-methylcoumarin | FhCatL2 | Fasciola hepatica |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
26000 | - |
x * 26000, mature enzyme, SDS-PAGE | Fasciola hepatica |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Fasciola hepatica | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
proteolytic modification | 38000 Da proenzyme, 26000 Da mature enzyme | Fasciola hepatica |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
benzyloxycarbonyl-Phe-Arg-7-amido-4-methylcoumarin + H2O | cathepsin L2 | Fasciola hepatica | benzyloxycarbonyl-Phe-Arg + 7-amino-4-methyl coumarin | - |
? | |
tosyl-Gly-Phe-Arg-7-amido-4-methylcoumarin + H2O | cathepsin L2 | Fasciola hepatica | tosyl-Gly-Phe-Arg + 7-amino-4-methylcoumarin | - |
? | |
tosyl-Gly-Pro-Arg-7-amido-4-methylcoumarin + H2O | cathepsin L2 | Fasciola hepatica | tosyl-Gly-Pro-Arg + 7-amino-4-methyl coumarin | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 26000, mature enzyme, SDS-PAGE | Fasciola hepatica |
Synonyms | Comment | Organism |
---|---|---|
cathepsin L2 | - |
Fasciola hepatica |
FhCatL2 | - |
Fasciola hepatica |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
26.3 | - |
tosyl-Gly-Phe-Arg-7-amido-4-methylcoumarin | FhCatL2 | Fasciola hepatica | |
50 | - |
benzyloxycarbonyl-Phe-Arg-7-amido-4-methylcoumarin | FhCatL2 | Fasciola hepatica | |
440 | - |
tosyl-Gly-Pro-Arg-7-amido-4-methylcoumarin | FhCatL2 | Fasciola hepatica |