Cloned (Comment) | Organism |
---|---|
recombinant expression of eimeripain fused to the fluorescent protein mCherry | Eimeria tenella |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
CA-074 | a specific cathepsin B inhibitor, the membrane-permeable derivative of CA-074, impairs invasion of epithelial MDBK cells by Eimeria tenella sporozoites | Eimeria tenella |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Eimeria tenella | G9IBU6 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
additional information | the enzyme is expressed throughout sporulation and has a punctate distribution in the bodies of extra- and intracellular parasites, expression profile, overview | Eimeria tenella | - |
oocyte | - |
Eimeria tenella | - |
sporozoite | extracellular and intracellular sporozoites | Eimeria tenella | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Z-Leu-Arg-7-amido-4-methylcoumarin + H2O | - |
Eimeria tenella | Z-Leu-Arg + 7-amino-4-methylcoumarin | - |
? | |
Z-Phe-Arg-7-amido-4-methylcoumarin + H2O | - |
Eimeria tenella | Z-Phe-Arg + 7-amino-4-methylcoumarin | - |
? |
Synonyms | Comment | Organism |
---|---|---|
cathepsin B-like cysteine protease | - |
Eimeria tenella |
eimeripain | - |
Eimeria tenella |
General Information | Comment | Organism |
---|---|---|
evolution | the enzyme is classified as a papain-like protease with similar characteristics to toxopain-1 from the related apicomplexan parasite, Toxoplasma gondii | Eimeria tenella |
additional information | enzyme catalytic domain homology modeling, overview | Eimeria tenella |