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Literature summary for 3.4.22.B50 extracted from

  • Chen, Z.; Wang, Y.; Ratia, K.; Mesecar, A.D.; Wilkinson, K.D.; Baker, S.C.
    Proteolytic processing and deubiquitinating activity of papain-like proteases of human coronavirus NL63 (2007), J. Virol., 81, 6007-6018.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Human coronavirus NL63
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
viral replicase polyprotein + H2O PLP2 is responsible for processing both cleavage sites 2 and 3 to release nsp2 and nsp3. The cleavage sites are identified as FTKLAG-/-GKISFS for CS2 and VAKQGA-/-GFKRTY for CS3. Human coronavirus NL63 ?
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Synonyms

Synonyms Comment Organism
PLP2
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Human coronavirus NL63