Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
cyclin D + H2O | Mus musculus | - |
? | - |
? | |
p21Cip1 + H2O | Mus musculus | - |
? | - |
? | |
p27Kip1 + H2O | Mus musculus | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
ATDC-5 cell | - |
Mus musculus | - |
chondrocyte | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
cyclin D + H2O | - |
Mus musculus | ? | - |
? | |
p21Cip1 + H2O | - |
Mus musculus | ? | - |
? | |
p27Kip1 + H2O | - |
Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
calpain small subunit | - |
Mus musculus |
Capn4 | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | deletion of calpain 4 leads to reduced chondrocyte proliferation and differentiation in embryonic growth plates. Deletion of calpain 4 in cells of the chondrocyte lineage correlated with impaired cell cycle progression at the G1/S transition, reduced cyclin D gene transcription | Mus musculus |
physiological function | calpain 4 is essential for proper chondrocyte functions in embryonic growth plates | Mus musculus |