Cloned (Comment) | Organism |
---|---|
expressed in Schizosaccharomyces pombe | Yersinia pestis |
Protein Variants | Comment | Organism |
---|---|---|
C172A | inactive | Yersinia pestis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Yersinia pestis | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
Yersinia outer protein J | - |
Yersinia pestis |
YopJ | - |
Yersinia pestis |
General Information | Comment | Organism |
---|---|---|
physiological function | when expressed in Schizosaccharomyces pombe, YopJ sensitizes cells to osmotic and oxidative stresses through a Hri2-dependent mechanism, however, when co-expressed with Yersinia protein kinase A, YopJ protects cells from Yersinia protein kinase A-mediated toxicity, and this protection is entirely dependent on Hri2. YopJ does not confer protection against the toxic effects of the Yersinia virulence factor YopE | Yersinia pestis |