Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Mus musculus C57/BL6J | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
bone marrow cell | - |
Mus musculus | - |
erythroid cell | - |
Mus musculus | - |
lymphoid cell | - |
Mus musculus | - |
myeloid cell | - |
Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
casp9 | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | loss of caspase-9 results in increased DNA damage and mutation burden after exposure to alkylating agents. Casp9 deficiency results in decreased erythroid and B-cell progenitor abundance and impaired function of hematopoietic stem cells after transplantation. Loss of Casp9 alters hematopoietic progenitor cell frequency | Mus musculus |
physiological function | caspase-9 is required for normal development of myeloid, lymphoid, and erythroid cells in mice. Role of caspase-9, the initiator caspase of the intrinsic apoptotic cascade, in murine fetal and adult hematopoiesis, overview | Mus musculus |