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Literature summary for 3.4.22.62 extracted from

  • Li, T.; Cui, Z.B.; Ke, X.X.; Tan, J.; Li, F.F.; Li, T.; Wang, X.W.; Cui, H.J.
    Essential role for p53 and caspase-9 in DNA damaging drug-induced apoptosis in neuroblastoma IMR32 cells (2011), DNA Cell Biol., 30, 1045-1050.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information activation of caspase-9 requires mitochondrial release of cytochrome c to the cytoplasm during apoptosis Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
-

Source Tissue

Source Tissue Comment Organism Textmining
IMR-32 cell
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Homo sapiens
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neuroblastoma cell
-
Homo sapiens
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General Information

General Information Comment Organism
metabolism p53 mediates DNA damaging drug-induced apoptosis in IMR32 cells through the caspase-9 pathway, molecular pathway, overview Homo sapiens
physiological function activation of caspase-9 requires mitochondrial release of cytochrome c to the cytoplasm during apoptosis Homo sapiens