Application | Comment | Organism |
---|---|---|
medicine | caspase-9 is a target for development of therapeutic approaches for histamine-related diseases | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
benzyloxycarbonyl-Leu-Glu-His-Asp-fluoromethylketone | - |
Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-histidine decarboxylase precursor + H2O | Mus musculus | in P-815 cells, histamine synthesis is augmented through the post-translational cleavage of L-histidine decarboxylase, which is mediated by caspase-9 | ? | - |
? | |
L-histidine decarboxylase precursor + H2O | Mus musculus BDF1 | in P-815 cells, histamine synthesis is augmented through the post-translational cleavage of L-histidine decarboxylase, which is mediated by caspase-9 | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
P-815 cell | mastocytoma | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-histidine decarboxylase precursor + H2O | - |
Mus musculus | ? | - |
? | |
L-histidine decarboxylase precursor + H2O | in P-815 cells, histamine synthesis is augmented through the post-translational cleavage of L-histidine decarboxylase, which is mediated by caspase-9 | Mus musculus | ? | - |
? | |
L-histidine decarboxylase precursor + H2O | - |
Mus musculus BDF1 | ? | - |
? | |
L-histidine decarboxylase precursor + H2O | in P-815 cells, histamine synthesis is augmented through the post-translational cleavage of L-histidine decarboxylase, which is mediated by caspase-9 | Mus musculus BDF1 | ? | - |
? |