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Literature summary for 3.4.22.62 extracted from
- Optical sensor for the detection of caspase-9 activity in a single cell (2004), J. Am. Chem. Soc., 126, 2799-2806.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| analysis | optical sensor for the detection of caspase-9 in a single cell. LEHD-7-amido-4-methylcoumarin covalently attached on the nanoprobe tip of the optical sensor is cleaved during apoptosis by caspase-9 generating free 7-amino-4-methylcoumarin | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| MCF-7 cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| LEHD-7-amido-4-methylcoumarin + H2O | - |
Homo sapiens | LEHD + 7-amino-4-methylcoumarin | - |
? |  |
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Release 2023.1 (January 2023)
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