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Literature summary for 3.4.22.61 extracted from

  • Oral, O.; Oz-Arslan, D.; Itah, Z.; Naghavi, A.; Deveci, R.; Karacali, S.; Gozuacik, D.
    Cleavage of Atg3 protein by caspase-8 regulates autophagy during receptor-activated cell death (2012), Apoptosis, 17, 810-820.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
Z-IETD caspase-8-specific inhibitor Homo sapiens
Z-VAD pan-caspase inhibitor Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Atg3 protein + H2O Homo sapiens
-
?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q14790
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Atg3 protein + H2O
-
Homo sapiens ?
-
?

General Information

General Information Comment Organism
physiological function cleavage of Atg3 protein by caspase-8 regulates autophagy during receptor-activated cell death Homo sapiens