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Literature summary for 3.4.22.61 extracted from

  • Al-Dhaheri, R.S.; Douglas, L.J.
    Apoptosis in Candida biofilms exposed to amphotericin B (2010), J. Med. Microbiol., 59, 149-157.
    View publication on PubMed
Search for more literature for 3.4.22.61

Inhibitors

Inhibitors Comment Organism Structure
benzyloxycarbonyl-IETD-fluoromethylketone specific caspase-8 inhibitor Candida albicans
benzyloxycarbonyl-IETD-fluoromethylketone specific caspase-8 inhibitor Candida parapsilosis
benzyloxycarbonyl-IETD-fluoromethylketone specific caspase-8 inhibitor Pichia kudriavzevii
benzyloxycarbonyl-VAD-fluoromethylketone pan-caspase inhibitor Candida albicans
benzyloxycarbonyl-VAD-fluoromethylketone pan-caspase inhibitor Candida parapsilosis
benzyloxycarbonyl-VAD-fluoromethylketone pan-caspase inhibitor Pichia kudriavzevii

Organism

Organism UniProt Comment Textmining
Candida albicans
-
-
-
Candida albicans GDH 2346
-
-
-
Candida parapsilosis
-
-
-
Candida parapsilosis AAHB 4479
-
-
-
Pichia kudriavzevii
-
-
-
Pichia kudriavzevii Glasgow
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(aspartyl)2-rhodamine 110 + H2O
-
 Pichia kudriavzevii ?
-
 ?
(aspartyl)2-rhodamine 110 + H2O
-
 Candida albicans ?
-
 ?
(aspartyl)2-rhodamine 110 + H2O
-
 Candida parapsilosis ?
-
 ?
(aspartyl)2-rhodamine 110 + H2O
-
 Pichia kudriavzevii Glasgow ?
-
 ?
(aspartyl)2-rhodamine 110 + H2O
-
 Candida parapsilosis AAHB 4479 ?
-
 ?
(aspartyl)2-rhodamine 110 + H2O
-
 Candida albicans GDH 2346 ?
-
 ?

General Information

General Information Comment Organism
malfunction caspase-8 inhibition decreases biofilm cell survival Pichia kudriavzevii
malfunction caspase-8 inhibition decreases biofilm cell survival Candida albicans
malfunction caspase-8 inhibition decreases biofilm cell survival Candida parapsilosis