Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | caspase-8 expression is increased in the orbito-frontal cortex 14 days after spared nerve injury of the sciatic nerve, prevented by ozone | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | high doses of ozone inhibit caspase-8 overexpression | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mus musculus | caspase-8 is a pro-apoptotic caspase, whose expression is increased in the orbito-frontal cortex 14 days after spared nerve injury of the sciatic nerve, prevented by ozone, regulation, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
astrocyte | - |
Mus musculus | - |
sciatic nerve | caspase-8 expression is increased in the orbito-frontal cortex 14 days after spared nerve injury of the sciatic nerve, prevented by ozone | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | caspase-8 is a pro-apoptotic caspase, whose expression is increased in the orbito-frontal cortex 14 days after spared nerve injury of the sciatic nerve, prevented by ozone, regulation, overview | Mus musculus | ? | - |
? |