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Literature summary for 3.4.22.61 extracted from

  • Fan, J.P.; Kim, H.S.; Han, G.D.
    Induction of apoptosis by L-carnitine through regulation of two main pathways in Hepa1c1c 7 cells (2009), Amino Acids, 36, 365-372.
    View publication on PubMed
Search for more literature for 3.4.22.61

Activating Compound

Activating Compound Comment Organism Structure
additional information caspase-8 expression is induced by Fas, and L-carnitine induces Fas and caspase-8 Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Mus musculus 5829
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus mRNA and protein level of caspase-8 is closely related to cell apoptosis by a death ligand/receptor-dependent apoptosis pathway, increased by L-carnitine treatment, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Hepa-1c1c7 cell
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information mRNA and protein level of caspase-8 is closely related to cell apoptosis by a death ligand/receptor-dependent apoptosis pathway, increased by L-carnitine treatment, overview Mus musculus ?
-
 ?