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Literature summary for 3.4.22.61 extracted from
- Roles of caspase-8 and caspase-10 in innate immune responses to double-stranded RNA (2006), J. Immunol., 176, 4520-4524.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | caspase-8 mediates NF-kappa-B-dependent inflammatory responses in antiviral signaling | Homo sapiens |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Homo sapiens |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| D210A/D216A | cannot be cleaved to release death effector domains, overexpression inhibits the endothelial cell leukocyte adhesion molecule 1 promoter activation induced by Fas-associated death domain and receptor-interacting protein 1 | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | Q14790 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| HEK-293 cell | - |
Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| caspase-8 | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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