Crystallization (Comment) | Organism |
---|---|
crystallization of caspase-8 in complex with p35 protein from baculovirus, at 20°C by hanging-drop vapour diffusion | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
p35 | p35 protein from baculovirus inhibits in the active site through a covalent thioester linkage to p35. The p35 protein undergoes dramatic conformational changes on cleavage by the caspase. The repositioning of the amino terminus of p35 into the active site of the caspase eliminates solvent accessibility of the catalytic dyad | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |