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Literature summary for 3.4.22.60 extracted from

  • Svandova, E.; Lesot, H.; Vanden Berghe, T.; Tucker, A.S.; Sharpe, P.T.; Vandenabeele, P.; Matalova, E.
    Non-apoptotic functions of caspase-7 during osteogenesis (2014), Cell Death Dis., 5, e1366.
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
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Mus musculus 5737
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Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
bone the activated form of caspase-7 is detected from the beginning of ossification during embryonic development and persists postnatally in alveolar and mandibular bones as well as long bones of limbs Mus musculus
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General Information

General Information Comment Organism
malfunction enzyme-deficient mice show a significant decrease in mineral density of endochondral bones Mus musculus
physiological function caspase-7 influences intramembranous and endochondral bone development Mus musculus