Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.22.59 extracted from

  • Cho, J.H.; Lee, P.Y.; Son, W.C.; Chi, S.W.; Park, B.C.; Kim, J.H.; Park, S.G.
    Identification of the novel substrates for caspase-6 in apoptosis using proteomic approaches (2013), BMB Rep., 46, 588-593.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.22.59

Cloned(Commentary)

Cloned (Comment) Organism
recombinant DELTA23 caspase-6 and DELTA23 caspase-6 mutant C163S with C-terminal His-tag are expressed in Escherichia coli BL21 codon plus (DE3) RIL cells Homo sapiens

Protein Variants

Protein Variants Comment Organism
C163S inactive Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
Z-VEID-fluoromethylketone specific inhibitor Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
actin + H2O Homo sapiens
-
 ?
-
 ?
alpha-tubulin + H2O Homo sapiens
-
 ?
-
 ?
ezrin + H2O Homo sapiens
-
 ?
-
 ?
GEP100 + H2O Homo sapiens
-
 ?
-
 ?
herpesvirus associated ubiquitin-specific protease + H2O Homo sapiens
-
 ?
-
 ?
kinesin5B + H2O Homo sapiens
-
 ?
-
 ?
lamin A/C + H2O Homo sapiens
-
 ?
-
 ?
additional information Homo sapiens CLK3, alcohol dehydrogenase 4 and malate dehydrogenase 1B are not cleaved by caspase-6 ?
-
 ?
partitioning-defective 3-like protein splice variant c + H2O Homo sapiens
-
 ?
-
 ?
serologically defined colon cancer antigen 3 + H2O Homo sapiens
-
 ?
-
 ?
vimentin + H2O Homo sapiens
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens P55212
-
-

Purification (Commentary)

Purification (Comment) Organism
Ni-NTA agarose column chromatography Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
Hep-G2 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
actin + H2O
-
 Homo sapiens ?
-
 ?
alpha-tubulin + H2O
-
 Homo sapiens ?
-
 ?
ezrin + H2O
-
 Homo sapiens ?
-
 ?
GEP100 + H2O
-
 Homo sapiens ?
-
 ?
herpesvirus associated ubiquitin-specific protease + H2O
-
 Homo sapiens ?
-
 ?
kinesin5B + H2O
-
 Homo sapiens ?
-
 ?
lamin A/C + H2O
-
 Homo sapiens ?
-
 ?
additional information CLK3, alcohol dehydrogenase 4 and malate dehydrogenase 1B are not cleaved by caspase-6 Homo sapiens ?
-
 ?
partitioning-defective 3-like protein splice variant c + H2O
-
 Homo sapiens ?
-
 ?
serologically defined colon cancer antigen 3 + H2O
-
 Homo sapiens ?
-
 ?
vimentin + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
Cas6
-
 Homo sapiens