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Literature summary for 3.4.22.59 extracted from

  • Nassiri, M.; Woolery-Lloyd, H.; Ramos, S.; Jacob, S.E.; Gugic, D.; Viciana, A.; Romanelli, P.; Elgart, G.; Berman, B.; Vincek, V.
    Gene expression profiling reveals alteration of caspase 6 and 14 transcripts in normal skin of keloid-prone patients (2009), Arch. Dermatol. Res., 301, 183-188.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
caspase-6 expression analysis Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens caspase 6, an apoptosis-related cysteine peptidase, is upregulated in the skin of keloid prone patients. Caspase-6 plays a crucial role during apoptosis ?
-
?
periplakin + H2O Homo sapiens caspase 6 has a specific epidermal target which is periplakin ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
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gene CASP6
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Source Tissue

Source Tissue Comment Organism Textmining
fibroblast keloid fioblasts show a decreased expression of apoptosis-related genes compared to scars Homo sapiens
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keratinocyte
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Homo sapiens
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skin
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Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information caspase 6, an apoptosis-related cysteine peptidase, is upregulated in the skin of keloid prone patients. Caspase-6 plays a crucial role during apoptosis Homo sapiens ?
-
?
periplakin + H2O caspase 6 has a specific epidermal target which is periplakin Homo sapiens ?
-
?