Activating Compound | Comment | Organism | Structure |
---|---|---|---|
resveratrol | induces caspase-6-dependent cleavage of lamin A | Homo sapiens |
Application | Comment | Organism |
---|---|---|
medicine | critical role of caspase-6 and its cleavage of lamin A in apoptotic signaling triggered by resveratrol in the colon carcinoma cells | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
siRNA | silencing of caspase-6 expression | Homo sapiens | |
Z-Val-Ala-Asp-fluoromethylketone | - |
Homo sapiens | |
Z-VEID-fmk | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HCT-116 cell | variants p53+, p53-, Bax+, Bax- | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
lamin A + H2O | - |
Homo sapiens | ? | - |
? | |
VEID-7-amido-4-trifluoromethylcoumarin + H2O | - |
Homo sapiens | VEID + 7-amino-4-trifluoromethylcoumarin | - |
? |