Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.22.56 extracted from

  • Glazer, E.S.; Kaluarachchi, W.D.; Massey, K.L.; Zhu, C.; Curley, S.A.
    Bioengineered arginase I increases caspase-3 expression of hepatocellular and pancreatic carcinoma cells despite induction of argininosuccinate synthetase-1 (2010), Surgery, 148, 310-318.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.22.56

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Bid peptide + H2O Homo sapiens
-
 ?
-
 ?
procaspase-3 + H2O Homo sapiens
-
 caspase-3 + ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HEP-3B cell
-
 Homo sapiens
-
hepatoma cell
-
 Homo sapiens
-
PANC-1 cell
-
 Homo sapiens
-
pancreatic adenocarcinoma cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Bid peptide + H2O
-
 Homo sapiens ?
-
 ?
IETD-4-nitroanilide + H2O
-
 Homo sapiens IETD + 4-nitroaniline
-
 ?
procaspase-3 + H2O
-
 Homo sapiens caspase-3 + ?
-
 ?

Expression

Organism Comment Expression
Homo sapiens there is an about 4fold increase of activated caspase-3 expression 4 days after high dose treatment with 100 nM L-arginase in Panc-1 and Hep-3B cells up