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Literature summary for 3.4.22.56 extracted from

  • Shen, L.; Zeng, S.; Chen, J.; Zhong, M.; Yang, H.; Yao, R.; Shen, H.
    E1A inhibits the proliferation of human cervical cancer cells (HeLa cells) by apoptosis induction through activation of HER-2/Neu/caspase-3 pathway (2008), Med. Oncol., 25, 222-228.
    View publication on PubMed
Search for more literature for 3.4.22.56

Activating Compound

Activating Compound Comment Organism Structure
additional information protein expression and activity of caspase-3 is upregulated by gene E1A, i.e. human adenovirus type 5 early region 1A, expression Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
caspase-3 expression analysis Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens human adenovirus type 5 early region 1A, E1A, significantly inhibits the cell proliferation of HeLa by the apoptosis induction through HER-2/Neu/caspase-3 pathway, overview ?
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 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HeLa cell
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 activity in HeLa cells Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
DEVD-4-nitroanilide + H2O
-
 Homo sapiens DEVD + 4-nitroaniline
-
 ?
additional information human adenovirus type 5 early region 1A, E1A, significantly inhibits the cell proliferation of HeLa by the apoptosis induction through HER-2/Neu/caspase-3 pathway, overview Homo sapiens ?
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Homo sapiens