Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Ac-DEVD-CHO | a caspase-3 inhibitor | Homo sapiens | |
additional information | processing of caspase-3 is affected only negligibly in cells treated with etoposide or N6-(2-isopentenyl)adenosine | Homo sapiens | |
N-alpha-tosyl-L-lysinyl-chloromethylketone | TLCK, a serine protease inhibitor and potent but nonspecific inhibitor of mature caspases, TLCK has no or only slight effect on caspase-3 processing, but TLCK substantially inhibits caspase-3 enzymatic DEVDase activity, but does not prevent cells from death | Homo sapiens | |
N-tosyl-L-phenylalaninyl-chloromethylketone | TPCK, a serine protease inhibitor and potent but nonspecific inhibitor of mature caspases, enhances caspase-3 processing although it substantially inhibits caspase-3 enzymatic DEVDase activity in HL-60 cells exposed to various cell death inducing stimuli, but does not prevent cells from death, overview | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HL-60 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Ac-DEVD-7-amido-4-methylcoumarin + H2O | - |
Homo sapiens | Ac-DEVD + 7-amino-4-methylcoumarin | - |
? |
Synonyms | Comment | Organism |
---|---|---|
DEVDase | - |
Homo sapiens |