Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | lipopeptide from the producing strain Bacillus natto TK-1, from the traditional Japanese food natto, induces caspase-3 activation | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
benzyloxycarbonyl-Val-Ala-Asp(OMe)-fluoromethylketone | a specific caspase 3 inhibitor | Homo sapiens | |
benzyloxycarbonyl-Val-Ala-DL-Asp-fluoromethylketone | a general caspase inhibitor | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | lipopeptide-induced apoptosis in MCF-7 cells is associated with caspase-3 | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
breast cancer cell | - |
Homo sapiens | - |
MCF-7 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | lipopeptide-induced apoptosis in MCF-7 cells is associated with caspase-3 | Homo sapiens | ? | - |
? | |
N-acetyl-Asp-Glu-Val-Asp 4-nitroanilide + H2O | - |
Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
caspase 3 | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
assay at | Homo sapiens |