Literature summary for 3.4.22.56 extracted from

Perry, D.K.; Smyth, M.J.; Stennicke, H.R.; Salvesen, G.S.; Duriez, P.; Poirier, G.G.; Hannun, Y.A.
Zinc is a potent inhibitor of the apoptotic protease, caspase-3. A novel target for zinc in the inhibition of apoptosis (1997), J. Biol. Chem., 272, 18530-18533.

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Inhibitors

Inhibitors	Comment	Organism	Structure
Cd2+	-	Homo sapiens
Hg2+	-	Homo sapiens
Zn2+	-	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
MOLT-4 cell	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
acetyl-DEVD-4-nitroanilide + H2O	-	Homo sapiens	acetyl-DEVD + 4-nitroaniline	-	?
poly(ADP-ribose) polymerase + H2O	bovine poly(ADP-ribose) polymerase	Homo sapiens	?	-	?

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Release 2023.1 (January 2023)