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Literature summary for 3.4.22.56 extracted from

  • Essmann, F.; Wieder, T.; Otto, A.; Muller, E.C.; Dorken, B.; Daniel, P.T.
    GDP dissociation inhibitor D4-GDI (Rho-GDI 2), but not the homologous rho-GDI 1, is cleaved by caspase-3 during drug-induced apoptosis (2000), Biochem. J., 346, 777-783.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.22.56

Inhibitors

Inhibitors Comment Organism Structure
benzyloxycarbonyl-DEVD-fluoromethylketone
-
 Homo sapiens
benzyloxycarbonyl-WEHD-fluoromethylketone
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
D4-GDI(Rho-GDI 2) + H2O Homo sapiens differential regulation of the homologous GDP dissociation inhibitors Rho-GDI 1 and D4-GDI during drug-induced apoptosis by proteolysis mediated by caspase-3 ?
-
 ?
Rho-GDI 1 + H2O Homo sapiens differential regulation of the homologous GDP dissociation inhibitors Rho-GDI 1 and D4-GDI during drug-induced apoptosis by proteolysis mediated by caspase-3 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
BJAB cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-DEVD-4-nitroanilide + H2O
-
 Homo sapiens acetyl-DEVD + 4-nitroaniline
-
 ?
D4-GDI(Rho-GDI 2) + H2O differential regulation of the homologous GDP dissociation inhibitors Rho-GDI 1 and D4-GDI during drug-induced apoptosis by proteolysis mediated by caspase-3 Homo sapiens ?
-
 ?
poly(ADP-ribose) polymerase + H2O
-
 Homo sapiens ?
-
 ?
Rho-GDI 1 + H2O differential regulation of the homologous GDP dissociation inhibitors Rho-GDI 1 and D4-GDI during drug-induced apoptosis by proteolysis mediated by caspase-3 Homo sapiens ?
-
 ?