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BRENDA support

Literature summary for 3.4.22.56 extracted from

  • Samejima, K.; Svigen, P.A.; Basi, G.S.; Kottke, T.; Mesner, P.W.; Stewart, L.; Durrieu, F.; Poirier, G.G.; Alnemri, E.S.; Champoux, J.J.; Kaufmann, S.H.; Earnshaw, W.C.
    caspase-mediated cleavage of DNA topoisomerase I at unconventional sites during apoptosis (1999), J. Biol. Chem., 274, 4335-4340.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
topoisomerase I + H2O Homo sapiens cleavage at DDVD146-/-Y and EEED170-/-G ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
topoisomerase I + H2O cleavage at DDVD146-/-Y and EEED170-/-G Homo sapiens ?
-
?