Protein Variants | Comment | Organism |
---|---|---|
C320A | catalytically inactive | Mus musculus |
S139An | expression of mutant S139A leads to significantly enhanced growth rate of cells | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | P29594 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
MEF cell | - |
Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
Casp2 | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
physiological function | caspase-2 is involved in apoptosis, nuclear factor-kappaB regulation, and tumor suppression. Caspase-2 catalytic site Cys-320 and Ser-139 residues are required for caspase-2 to suppress tumorigenesis in nude mice | Mus musculus |