Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Z-Val-Asp-Val-Ala-Asp-fluoromethylketone | - |
Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
33000 | - |
x * 33000, active subunit | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
proteolytic modification | caspase-2 processing occurs in goniothalamin-treated Jurkat cells, cleavage to its active subunit (33 kDa) occurs as early as 3 h | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
JURKAT E-6.1 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Val-Asp-Val-Ala-Asp-7-amido-4-methylcoumarin + H2O | - |
Homo sapiens | Val-Asp-Val-Ala-Asp + 7-amino-4-methylcoumarin | - |
? | |
Val-Asp-Val-Ala-Asp-7-amido-4-trifluoromethylcoumarin + H2O | - |
Homo sapiens | Val-Asp-Val-Ala-Asp + 7-amino-4-trifluoromethylcoumarin | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 33000, active subunit | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
caspase-2 | - |
Homo sapiens |