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Literature summary for 3.4.22.55 extracted from

  • Taghiyev, A.F.; Guseva, N.V.; Glover, R.A.; Rokhlin, O.W.; Cohen, M.B.
    TSA-induced cell death in prostate cancer cell lines is caspase-2 dependent and involves the PIDDosome (2006), Cancer Biol. Ther., 5, 1199-1205.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Homo sapiens 5829
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens caspase-2 initiates caspase cascade after trichostatin A treatment and involves the formation of the PIDDosome (a complex of caspase-2-CRADD/RAIDD-PIDD) ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
DU-145 cell
-
Homo sapiens
-
LNCaP cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information caspase-2 initiates caspase cascade after trichostatin A treatment and involves the formation of the PIDDosome (a complex of caspase-2-CRADD/RAIDD-PIDD) Homo sapiens ?
-
?