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Literature summary for 3.4.22.53 extracted from

  • Maddock, K.R.; Huff-Lonergan, E.; Rowe, L.J.; Lonergan, S.M.
    Effect of pH and ionic strength on mu- and m-calpain inhibition by calpastatin (2005), J. Anim. Sci., 83, 1370-1376.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
calpastatin inhibition of m-calpain is greater at pH 7.5 than at pH 6.5 at both 165 mM and 295 mM NaCl. Percentage inhibition is greater at 295 mM than at 165 mM NaCl Sus scrofa
NaCl m-calpain is more active at 165 mM NaCl than at 295 mM NaCl Sus scrofa

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
skeletal muscle
-
Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
succinyl-Leu-Leu-Val-Tyr-7-amido-4-methylcoumarin + H2O
-
Sus scrofa ?
-
?

Synonyms

Synonyms Comment Organism
m-calpain
-
Sus scrofa

pH Range

pH Minimum pH Maximum Comment Organism
6.5 7.5 activity of m-calpain is greater at pH 7.5 than at pH 6.5 Sus scrofa