Inhibitors | Comment | Organism | Structure |
---|---|---|---|
calpastatin | - |
Mus musculus | |
calpeptin | - |
Mus musculus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
80000 | - |
x * 80000, SDS-PAGE | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
neural stem cell | - |
Mus musculus | - |
Subunits | Comment | Organism |
---|---|---|
? | x * 80000, SDS-PAGE | Mus musculus |
Synonyms | Comment | Organism |
---|---|---|
calpain 1 | - |
Mus musculus |
CAPN1 | - |
Mus musculus |
Organism | Comment | Expression |
---|---|---|
Mus musculus | calpain 1 expression levels are high in self-renewing neuronal stem cells and decrease with differentiation | up |
General Information | Comment | Organism |
---|---|---|
malfunction | calpain inhibition favors differentiation of neuronal stem cells. Calpain 1 silencing results in increased levels of both neuronal and glial markers, beta-III tubulin and glial fibrillary acidic protein | Mus musculus |
physiological function | calpain 1 plays a role in repressing differentiation, thus maintaining a proliferative neuronal stem cell pool | Mus musculus |