Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,2-bis(o-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid tetra(acetoxymethyl) ester | - |
Rattus norvegicus | |
acetyl-Leu-Leu-Met-CHO | - |
Rattus norvegicus | |
acetyl-Leu-Leu-Nle-CHO | - |
Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
PC-12 cell | - |
Rattus norvegicus | - |
Synonyms | Comment | Organism |
---|---|---|
calpain 1 | - |
Rattus norvegicus |
Organism | Comment | Expression |
---|---|---|
Rattus norvegicus | calpain activity increases in cells exposed to intermittent hypoxia 60 and 0.01 mM 1,2-bis(o-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid tetra(acetoxymethyl) ester prevents this effect | down |
Rattus norvegicus | ionomycin and thapsigragin, which elevate [Ca2+], activate calpains in cells exposed to normoxia | up |
General Information | Comment | Organism |
---|---|---|
physiological function | calpain 1 activation contributes to HIF-2alpha degradation by IH | Rattus norvegicus |