Inhibitors | Comment | Organism | Structure |
---|---|---|---|
calpastatin | - |
Rattus norvegicus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | calpain I is a calcium-dependent protease | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cerebral cortical neuron | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
apoptosis-inducing factor + H2O | calpain-mediated truncation of apoptosis-inducing factor is contingent upon poly(ADP-ribose) polymerase-1 activity | Rattus norvegicus | ? | - |
? | |
E-(EDANS)-PLFAERK-(Dabcyl) + H2O | - |
Rattus norvegicus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
calpain I | - |
Rattus norvegicus |
General Information | Comment | Organism |
---|---|---|
malfunction | calpain inhibition prevents NMDA-induced AIF truncation and nuclear translocation in neurons | Rattus norvegicus |