Application | Comment | Organism |
---|---|---|
medicine | mu-calpain is a marker of tumor aggressiveness and is apotential target for limiting development of rhabdomyosarcoma tumor as well as their metastatic behavior | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
calpeptin | Z-Leu-Nle-CHO | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | calcium-dependent cysteine protease | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
LHCN-M2 cell | - |
Homo sapiens | - |
rhabdomyosarcoma cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
tert-butyloxycarbonyl-L-leucyl-L-methionine-7-amido-4-chloromethylcoumarin + H2O | - |
Homo sapiens | tert-butyloxycarbonyl-L-leucyl-L-methionine + 7-amino-4-chloromethylcoumarin | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CAPN1 | - |
Homo sapiens |
mu-calpain | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | mu-calpain up-regulates alpha- and beta-actin in alveolar rhabdomyosarcoma cells | Homo sapiens |