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Literature summary for 3.4.22.52 extracted from

  • Zhang, J.; Miyamoto, K.I.; Hashioka, S.; Hao, H.P.; Murao, K.; Saido, T.C.; Nakanishi, H.
    Activation of m-calpain in developing cortical neurons following methylmercury treatment (2003), Brain Res. Dev. Brain Res., 142, 105-110.
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
alpha-spectrin + H2O Rattus norvegicus mu-calpain is neuroprotective in the early stage of excitotoxic injury. Activation and proteolysis of alpha-spectrin by mu-calpain preceds neuronal damage in the developing cerebral cortex induced by chronic treatament of methylmercury ?
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 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cerebral cortex
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alpha-spectrin
-
 Rattus norvegicus ?
-
 ?
alpha-spectrin + H2O mu-calpain is neuroprotective in the early stage of excitotoxic injury. Activation and proteolysis of alpha-spectrin by mu-calpain preceds neuronal damage in the developing cerebral cortex induced by chronic treatament of methylmercury Rattus norvegicus ?
-
 ?