Literature summary for 3.4.22.51 extracted from

Huson, L.E.; Authie, E.; Boulange, A.F.; Goldring, J.P.; Coetzer, T.H.
Modulation of the immunogenicity of the Trypanosoma congolense cysteine protease, congopain, through complexation with alpha2-macroglobulin (2009), Vet. Res., 40, 52.

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Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	in general immunoglobulin G fractions isolated from rabbits immunised with rabbit apha2-macroglobulin-recombinant catalytic domain of congopain-complexes are the most inhibitory towards the proteolytic activity of congopain. Antibodies produced by rabbits immunised with recombinant catalytic domain of congopain in Freund's adjuvant are generally found to weakly inhibit congopain with a maximum of 40%	Trypanosoma congolense

Organism

Organism	UniProt	Comment	Textmining
Trypanosoma congolense	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Trypanosoma congolense

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
benzyloxycarbonyl-Phe-Arg-7-amido-4-methylcoumarin + H2O	-	Trypanosoma congolense	benzyloxycarbonyl-Phe-Arg + 7-amino-4-methylcoumarin	-	?

Synonyms

Synonyms	Comment	Organism
congopain	-	Trypanosoma congolense

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Release 2023.1 (January 2023)