Inhibitors | Comment | Organism | Structure |
---|---|---|---|
chagasin | - |
Trypanosoma cruzi | |
chagasin mutant delta T31-T32 | - |
Trypanosoma cruzi | |
chagasin mutant P30A | - |
Trypanosoma cruzi | |
chagasin mutant T31A | - |
Trypanosoma cruzi | |
chagasin mutant T31A/T32A | - |
Trypanosoma cruzi | |
chagasin mutant T31S | - |
Trypanosoma cruzi | |
chagasin mutant T31V | - |
Trypanosoma cruzi | |
chagasin mutant T31Y | - |
Trypanosoma cruzi | |
chagasin mutant T32A | - |
Trypanosoma cruzi | |
chagasin mutant T32E | - |
Trypanosoma cruzi | |
chagasin mutant T32S | - |
Trypanosoma cruzi | |
chagasin mutant T32V | - |
Trypanosoma cruzi | |
chagasin mutant T32Y | - |
Trypanosoma cruzi | |
chagasin mutant W93A | - |
Trypanosoma cruzi | |
chagasin mutant Y89F | - |
Trypanosoma cruzi | |
chagasin mutant Y89S | - |
Trypanosoma cruzi |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Trypanosoma cruzi | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Z-Phe-Arg-7-amido-4-methylcoumarin + H2O | 5 microM, pH 6.5, 28°C | Trypanosoma cruzi | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
cruzipain | - |
Trypanosoma cruzi |
family C1 cysteine peptidase | - |
Trypanosoma cruzi |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
28 | - |
assay at pH 6.5 | Trypanosoma cruzi |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.5 | - |
assay at 28°C | Trypanosoma cruzi |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0000000076 | - |
chagasin | - |
Trypanosoma cruzi | |
0.000000011 | - |
chagasin mutant T31S | - |
Trypanosoma cruzi | |
0.000000011 | - |
chagasin mutant T32E | - |
Trypanosoma cruzi | |
0.000000016 | - |
chagasin mutant T32A | - |
Trypanosoma cruzi | |
0.000000016 | - |
chagasin mutant T32Y | - |
Trypanosoma cruzi | |
0.00000002 | - |
chagasin mutant P30A | - |
Trypanosoma cruzi | |
0.00000002 | - |
chagasin mutant T32S | - |
Trypanosoma cruzi | |
0.00000002 | - |
chagasin mutant Y89F | - |
Trypanosoma cruzi | |
0.000000025 | - |
chagasin mutant Y89S | - |
Trypanosoma cruzi | |
0.000000031 | - |
chagasin mutant W93A | - |
Trypanosoma cruzi | |
0.00000007 | - |
chagasin mutant T31V | - |
Trypanosoma cruzi | |
0.000000193 | - |
chagasin mutant T32V | - |
Trypanosoma cruzi | |
0.000000317 | - |
chagasin mutant T31A | - |
Trypanosoma cruzi | |
0.000000747 | - |
chagasin mutant T31Y | - |
Trypanosoma cruzi | |
0.000001065 | - |
chagasin mutant T31A/T32A | - |
Trypanosoma cruzi | |
0.000005868 | - |
chagasin mutant deltaT31-T32 | - |
Trypanosoma cruzi |