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Literature summary for 3.4.22.51 extracted from
- Angiotensin-converting enzyme limits inflammation elicited by Trypanosoma cruzi cysteine proteases: a peripheral mechanism regulating adaptive immunity via the innate kinin pathway (2008), Biol. Chem., 389, 1015-1024.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| heparan sulfate | 6-fold increased catalytic efficiency | Trypanosoma cruzi |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| captopril | - |
Trypanosoma cruzi | |
| chagasin | - |
Trypanosoma cruzi |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| flagellar pocket | - |
Trypanosoma cruzi | - |
- |
| lysosome | isoform 1 | Trypanosoma cruzi | 5764 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Trypanosoma cruzi | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| cruzipain | isoform I and II | Trypanosoma cruzi |
| CTE-truncated recombinant protease | - |
Trypanosoma cruzi |
| kinin-releasing cysteine proteases | - |
Trypanosoma cruzi |
| lysosomal-like cysteine protease | - |
Trypanosoma cruzi |
pH Stability
| pH Stability | pH Stability Maximum | Comment | Organism |
|---|---|---|---|
| additional information | - |
enzymatically active and stable in neutral/acidic pH | Trypanosoma cruzi |
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Release 2023.1 (January 2023)
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